Upending decades-old dogma, a team of scientists at the University of California, San Diego School of Medicine say enzymes long categorized as promoting cancer are, in fact, tumor suppressors and that current clinical efforts to develop inhibitor-based drugs should instead focus on restoring the enzymes’ activities.
http://ucsdnews.ucsd.edu/pressrelease/enzymes_believed_to_promote_cancer_actually_suppress_tumors